Kangenkaryu Prevents the Decrease of Cholinergic Markers Following the Nucleus Basalis Magnocellularis Lesion.
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چکیده
منابع مشابه
Kangenkaryu prevents the decrease of cholinergic markers following the nucleus basalis magnocellularis lesion.
The nucleus basalis magnocellularis (nbm)-lesioned rat is considered to be a model of the cholinergic dysfunction observed in the cerebral cortices of Alzheimer's disease patients. The cholinergic markers, acetylcholine release and choline acetyltransferase activity, were decreased in the cerebral cortex of the nbm-lesioned rat. Kangenkaryu (KAN), a Chinese traditional medicine, is a typical pr...
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The effects on anatomy and behavior of a ribosomal inactivating protein (saporin) coupled to a monoclonal antibody against the low-affinity NGF receptor (NGFr) were examined. In adult rats, NGFr is expressed predominantly in cholinergic neurons of the medial septal area (MSA), diagonal band nuclei, and nucleus basalis magnocellularis (nBM), but also in noncholinergic cerebellar Purkinje cells. ...
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The ability of acetylcholine (ACh) to alter specific functional properties of the cortex endows the cholinergic system with an important modulatory role in memory formation. For example, an increase in ACh release occurs during novel stimulus processing, indicating that ACh activity is critical during early stages of memory processing. During novel taste presentation, there is an increase in AC...
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ژورنال
عنوان ژورنال: The Japanese Journal of Pharmacology
سال: 1992
ISSN: 0021-5198,1347-3506
DOI: 10.1254/jjp.60.307